From: Vlad Cojocaru (
Date: Sat Mar 19 2016 - 03:34:16 CDT

Chimera can do that nicely ... the command is "swapna" (see chimera
user guide) .. I don't think VMD can do it (but I may have missed this
feature if it exists)


On 03/19/2016 08:32 AM, Kalyanashis Jana wrote:
> Hi,
> I am Kalyanashis Jana, working under Dr. Bishwajit Ganguly,
> CSIR-CSMCRI, Bhavnagar, India. I used the VMD mutation technique for
> protein system. However, it was not working for some specific amino
> acid residues e.g. histidine, selenocysteine. Otherwise, it is an
> excellent platform to mutate protein or enzyme. Now, I would like to
> mutate DNA or RNA i.e. I would like to replace a single/multiple
> nucleobase with other DNA/RNA nucleobase(s). Can you please tell me,
> is it possible to mutate DNA/RNA with VMD?
> Looking forward to hear from you positively.
> Thanks in advance,
> With best regards
> Kalyanashis Jana

Dr. Vlad Cojocaru
Computational Structural Biology Laboratory
Department of Cell and Developmental Biology
Max Planck Institute for Molecular Biomedicine
Röntgenstrasse 20, 48149 Münster, Germany
Tel: +49-251-70365-324; Fax: +49-251-70365-399
Email: vlad.cojocaru[at]